Name: chitosan-based systems for biopharmaceuticals: delivery, targeting and polymer therapeutics
Price: 2954.21 MXN
Availability: InStock
Author: bruno sarmento, jose das neves
ISBN: 9780470978320

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portada chitosan-based systems for biopharmaceuticals: delivery, targeting and polymer therapeutics

Formato

Libro Físico

Editorial

wiley

Autor

bruno sarmento, jose das neves

N° páginas

584

ISBN

0470978325

ISBN13

9780470978320

Categorías

Farmacología

chitosan-based systems for biopharmaceuticals: delivery, targeting and polymer therapeutics

Bruno Sarmento, Jose Das Neves (Autor) · wiley · Libro Físico

Libro Físico

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Origen: Reino Unido (Costos de importación incluídos en el precio)

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Reseña del libro "chitosan-based systems for biopharmaceuticals: delivery, targeting and polymer therapeutics"

chitosan is a linear polysaccharide produced commercially by the deacetylation of chitin. it is non-toxic, biodegradable, biocompatible, and acts as a bioadhesive with otherwise unstable biomolecules - making it a valuable component in the formulation of biopharmaceutical drugs. chitosan-based systems for biopharmaceuticals provides an extensive overview of the application of chitosan and its derivatives in the development and optimisation of biopharmaceuticals. the book is divided in four different parts. part i discusses general aspects of chitosan and derivatives, with particular emphasis on issues related to the development of biopharmaceutical chitosan-based systems, comprising a useful background for the following chapters. part ii deals with the use of chitosan and derivatives in the formulation and delivery of biopharmaceuticals, and focuses on the synergistic effects between chitosan and this particular subset of pharmaceuticals. part iii continues and complements the previous part by discussing in detail specific applications of chitosan and/or some particular derivatives for biopharmaceutical use. finally, part iv presents diverse viewpoints on different issues such as regulatory, manufacturing and toxicological requirements of chitosan and its derivatives related with the development of biopharmaceutical products, as well as their patent status, and clinical application and potential. topics covered include: chemical and technological advances in chitins and chitosans useful for the formulation of biopharmaceuticals physical properties of chitosan and derivatives in sol and gel states absorption promotion properties of chitosan and derivatives biocompatibility and biodegradation of chitosan and derivatives biological and pharmacological activity of chitosan and derivatives biological, chemical and physical compatibility of chitosan and biopharmaceuticals approaches for functional modification or crosslinking of chitosan use of chitosan and derivatives in conventional biopharmaceutical dosage forms formulation manufacture techniques of chitosan-based microparticles and nanoparticles for biopharmaceuticals chitosan and derivatives for biopharmaceutical use: mucoadhesive properties chitosan-based systems for mucosal delivery of biopharmaceuticals chitosan-based delivery systems for mucosal vaccination chitosan-based nanoparticulates for oral delivery of biopharmaceuticals chitosan-based systems for ocular delivery of biopharmaceuticals chemical modification of chitosan for delivery of dna and sirna target-specific chitosan-based nanoparticle systems for nucleic acid delivery functional pegylated chitosan systems for biopharmaceuticals stimuli-sensitive chitosan-based systems for biopharmaceuticals chitosan copolymers for biopharmaceuticals application of chitosan for anti-cancer biopharmaceutical delivery chitosan-based biopharmaceuticals scaffolds in tissue engineering and regenerative medicine wound healing properties of chitosan and its use in wound dressing biopharmaceuticals toxicological properties of chitosan and derivatives for biopharmaceutical applications regulatory status of chitosan and derivatives patentability and intellectual property issues related with chitosan-based biopharmaceutical products quality control and good manufacturing practice (gmp) for chitosan-based biopharmaceutical products preclinical and clinical use of chitosan and derivatives for biopharmaceuticals: from preclinical research to the bedside chitosan-based systems for biopharmaceuticals is an important compendium of fundamental concepts and practical tools and applications of chitosan-based biopharmaceuticals for researchers in academia and industry working in drug formulation and delivery, biopharmaceuticals, medicinal chemistry, pharmacy, bioengineering and new materials development.