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nuclear organization in development and disease: novartis foundation symposium, no. 264
Novartis Foundation (Autor)
·
wiley
· Libro Físico
nuclear organization in development and disease: novartis foundation symposium, no. 264 - novartis foundation
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Reseña del libro "nuclear organization in development and disease: novartis foundation symposium, no. 264"
this book draws together contributions from cell and developmental biologists, structural biologists, geneticists and clinical scientists interested in the cellular and molecular basis of these diseases. topics include how nuclear structure and location within a nucleus affect gene expression, chromatin organization and cell differentiation; the nature of the interactions between the nuclear envelope and the cytoskeleton; the extent to which the cytoskeleton mediates communication between the cell membrane and nucleus in regulating gene expression and whether disruption of such communication might underlie the disease processes. it is hoped that a better understanding of the mechanisms leading to disease pathogenesis may ultimately result in more rational and appropriate treatments.
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