Name: One-Step Generation of a Drug-Releasing Microarray for High-Throughput Small-Volume Bioassays (en Inglés)
Price: 2574.71 MXN
Availability: InStock
Author: Song, Seo Woo
ISBN: 9789811380969

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portada One-Step Generation of a Drug-Releasing Microarray for High-Throughput Small-Volume Bioassays (en Inglés)

Formato

Libro Físico

Autor

Seo Woo Song

Editorial

Springer

Idioma

Inglés

N° páginas

Encuadernación

Tapa Blanda

Dimensiones

23.4 x 15.6 x 0.4 cm

Peso

0.12 kg.

ISBN13

9789811380969

Categorías

Génetica médica
Ingeniería biomédica
Mecánica de fluidos
Biotecnología
Mecánica de fluidos aplicada

One-Step Generation of a Drug-Releasing Microarray for High-Throughput Small-Volume Bioassays (en Inglés)

Seo Woo Song (Autor) · Springer · Tapa Blanda

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Origen: Estados Unidos (Costos de importación incluídos en el precio)

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Reseña del libro "One-Step Generation of a Drug-Releasing Microarray for High-Throughput Small-Volume Bioassays (en Inglés)"

This thesis demonstrates a technology that enables pipetting-free high-throughput screening (HTS) on a miniaturized platform, eliminating the need for thousands of one-by-one pipetting and conventional liquid handling systems. This platform enhances accessibility to HTS and enables HTS to be used in small-to-medium scale laboratories. In addition, it allows large-scale combinatorial screening with a small number of valuable cells, such as patients' primary cancer cells. This technique will have a high impact for widespread use of HTS in the era of personalized medicine. In this thesis, the author firstly describes the need and concept of 'partipetting' for pipetting-free HTS platform. It is realized by the one-step pipetting and self-assembly of encoded drug-laden microparticles (DLPs) on the microwells. Next, the technical implementations required for the platform demonstration are described. It includes preparation of encoded DLPs, plastic chip fabrication, andrealization of automated system. Lastly, screening of sequential drug combinations using this platform is demonstrated. This shows the potential of the proposed technology for various applications.